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Angiotensin 1–7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression

The present study aimed to investigate the effects of angiotensin (Ang) 1–7 on caerulein (CAE)-stimulated nuclear factor (NF)-κB, Toll-like receptor (TLR4) and cytokine expression using pancreatic acinar AR42J cells. AR42J cells were treated with 10 nmol/l CAE for various durations. In addition, cel...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Wang, Guoxing, Cui, Lijian, Liu, Ruixia, Xiao, Hongli, Yin, Chenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802148/
https://www.ncbi.nlm.nih.gov/pubmed/29286117
http://dx.doi.org/10.3892/mmr.2017.8354