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Treatment with Shuyu capsule increases 5-HT1AR level and activation of cAMP-PKA-CREB pathway in hippocampal neurons treated with serum from a rat model of depression

Depressive disorder (DD) is one of the typical affective disorders with a high morbidity, high suicide rate and high recurrence rate. Dysfunction of the 5-hydroxytryptamine 1A receptor (5-HT1AR) in the brain may serve an important role in the pathogenesis of DD. Currently, selective serotonin reupta...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Long, Gao, Jie, Wang, Xiao-Yu, Mu, Xiao-Fei, Wei, Sheng, Xue, Ling, Qiao, Ming-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802157/
https://www.ncbi.nlm.nih.gov/pubmed/29286104
http://dx.doi.org/10.3892/mmr.2017.8339

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