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Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cells

Histone deacetylase inhibitors (HDACIs) cause oncogene-transformed mammalian cell death. Our previous study indicated that HDACIs activate forkhead box O1 (FOXO1) and induce autophagy in liver and colon cancer cells. However, whether FOXO1 is involved in HDACI-mediated oncogene-transformed mammalian...

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Detalles Bibliográficos
Autores principales:	Gao, Liang, Sun, Xin, Zhang, Qi, Chen, Xiaochen, Zhao, Tongwei, Lu, Liqing, Zhang, Jianbin, Hong, Yupeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802205/ https://www.ncbi.nlm.nih.gov/pubmed/29344672 http://dx.doi.org/10.3892/mmr.2018.8446

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