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Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
A G-rich nucleic acid-tethered acrylamide/N-isopropylacrylamide (NIPAM) copolymer is prepared. The nucleic acid-modified pNIPAM chains assemble, in the presence of K(+) ions, into a stimuli-responsive G-quadruplex-crosslinked pNIPAM hydrogel undergoing cyclic and reversible solution/hydrogel/solid t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802269/ https://www.ncbi.nlm.nih.gov/pubmed/29435215 http://dx.doi.org/10.1039/c5sc02203g |
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author | Lu, Chun-Hua Guo, Weiwei Qi, Xiu-Juan Neubauer, Avner Paltiel, Yossi Willner, Itamar |
author_facet | Lu, Chun-Hua Guo, Weiwei Qi, Xiu-Juan Neubauer, Avner Paltiel, Yossi Willner, Itamar |
author_sort | Lu, Chun-Hua |
collection | PubMed |
description | A G-rich nucleic acid-tethered acrylamide/N-isopropylacrylamide (NIPAM) copolymer is prepared. The nucleic acid-modified pNIPAM chains assemble, in the presence of K(+) ions, into a stimuli-responsive G-quadruplex-crosslinked pNIPAM hydrogel undergoing cyclic and reversible solution/hydrogel/solid transitions. Addition of kryptofix [2.2.2], CP, to the K(+)-stabilized G-quadruplex-crosslinked hydrogel eliminates the K(+) ions from the crosslinking units, resulting in the transition of the hydrogel into a pNIPAM solution. In turn, heating the pNIPAM hydrogel from 25 °C to 40 °C results in the transition of the hydrogel to the solid state, and cooling the solid to 25 °C restores the hydrogel state. Incorporation of hemin into the G-quadruplex-crosslinked hydrogel results in a catalytic hydrogel that catalyzes the oxidation of aniline by H(2)O(2) to form polyaniline. The polyaniline/pNIPAM hydrogel hybrid doped with 2 M HCl forms an emeraldine salt, which exhibits an electrical conductivity of 9 × 10(–4) [cm Ω](–1). |
format | Online Article Text |
id | pubmed-5802269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-58022692018-02-12 Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline Lu, Chun-Hua Guo, Weiwei Qi, Xiu-Juan Neubauer, Avner Paltiel, Yossi Willner, Itamar Chem Sci Chemistry A G-rich nucleic acid-tethered acrylamide/N-isopropylacrylamide (NIPAM) copolymer is prepared. The nucleic acid-modified pNIPAM chains assemble, in the presence of K(+) ions, into a stimuli-responsive G-quadruplex-crosslinked pNIPAM hydrogel undergoing cyclic and reversible solution/hydrogel/solid transitions. Addition of kryptofix [2.2.2], CP, to the K(+)-stabilized G-quadruplex-crosslinked hydrogel eliminates the K(+) ions from the crosslinking units, resulting in the transition of the hydrogel into a pNIPAM solution. In turn, heating the pNIPAM hydrogel from 25 °C to 40 °C results in the transition of the hydrogel to the solid state, and cooling the solid to 25 °C restores the hydrogel state. Incorporation of hemin into the G-quadruplex-crosslinked hydrogel results in a catalytic hydrogel that catalyzes the oxidation of aniline by H(2)O(2) to form polyaniline. The polyaniline/pNIPAM hydrogel hybrid doped with 2 M HCl forms an emeraldine salt, which exhibits an electrical conductivity of 9 × 10(–4) [cm Ω](–1). Royal Society of Chemistry 2015-11-01 2015-08-10 /pmc/articles/PMC5802269/ /pubmed/29435215 http://dx.doi.org/10.1039/c5sc02203g Text en This journal is © The Royal Society of Chemistry 2015 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0) |
spellingShingle | Chemistry Lu, Chun-Hua Guo, Weiwei Qi, Xiu-Juan Neubauer, Avner Paltiel, Yossi Willner, Itamar Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline |
title | Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
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title_full | Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
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title_fullStr | Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
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title_full_unstemmed | Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
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title_short | Hemin–G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline
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title_sort | hemin–g-quadruplex-crosslinked poly-n-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802269/ https://www.ncbi.nlm.nih.gov/pubmed/29435215 http://dx.doi.org/10.1039/c5sc02203g |
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