The nonlinear relationship between cerebrospinal fluid Aβ(42) and tau in preclinical Alzheimer’s disease

Cerebrospinal fluid (CSF) studies consistently show that CSF levels of amyloid-beta 1–42 (Aβ(42)) are reduced and tau levels increased prior to the onset of cognitive decline related to Alzheimer’s disease (AD). However, the preclinical prediction accuracy for low CSF Aβ(42) levels, a surrogate for...

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Detalles Bibliográficos
Autores principales: de Leon, Mony J., Pirraglia, Elizabeth, Osorio, Ricardo S., Glodzik, Lidia, Saint-Louis, Les, Kim, Hee-Jin, Fortea, Juan, Fossati, Silvia, Laska, Eugene, Siegel, Carole, Butler, Tracy, Li, Yi, Rusinek, Henry, Zetterberg, Henrik, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802432/
https://www.ncbi.nlm.nih.gov/pubmed/29415068
http://dx.doi.org/10.1371/journal.pone.0191240

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