CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles

Polycythemia vera (PV) and essential thrombocythemia (ET) are Philadelphia-negative myeloproliferative neoplasms (MPNs) characterized by erythrocytosis and thrombocytosis, respectively. Approximately 95% of PV and 50–70% of ET patients harbor the V617F mutation in the exon 14 of JAK2 gene, while abo...

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Detalles Bibliográficos
Autores principales: Zini, Roberta, Guglielmelli, Paola, Pietra, Daniela, Rumi, Elisa, Rossi, Chiara, Rontauroli, Sebastiano, Genovese, Elena, Fanelli, Tiziana, Calabresi, Laura, Bianchi, Elisa, Salati, Simona, Cazzola, Mario, Tagliafico, Enrico, Vannucchi, Alessandro M., Manfredini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802509/
https://www.ncbi.nlm.nih.gov/pubmed/29217833
http://dx.doi.org/10.1038/s41408-017-0010-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802509/
https://www.ncbi.nlm.nih.gov/pubmed/29217833
http://dx.doi.org/10.1038/s41408-017-0010-2

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