Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1

Studies of induced pluripotent stem cells (iPSCs) from schizophrenia patients and control individuals revealed that the disorder is programmed at the preneuronal stage, involves a common dysregulated mRNA transcriptome, and identified Integrative Nuclear FGFR1 Signaling a common dysregulated mechani...

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Detalles Bibliográficos
Autores principales: Stachowiak, E. K., Benson, C. A., Narla, S. T., Dimitri, A., Chuye, L. E. Bayona, Dhiman, S., Harikrishnan, K., Elahi, S., Freedman, D., Brennand, K. J., Sarder, P., Stachowiak, M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802550/
https://www.ncbi.nlm.nih.gov/pubmed/30446636
http://dx.doi.org/10.1038/s41398-017-0054-x

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