Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data

We have tested published methods for capturing allelic heterogeneity and identifying loci of joint effects to uncover more of the “hidden heritability” of schizophrenia (SCZ). We used two tools, cojo-GCTA and multi-SNP, to analyze meta-statistics from the latest genome-wide association study (GWAS)...

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Detalles Bibliográficos
Autores principales: Polushina, Tatiana, Giddaluru, Sudheer, Bettella, Francesco, Espeseth, Thomas, Lundervold, Astri J., Djurovic, Srdjan, Cichon, Sven, Hoffmann, Per, Nöthen, Markus M., Steen, Vidar M., Andreassen, Ole A., Le Hellard, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802566/
https://www.ncbi.nlm.nih.gov/pubmed/29249828
http://dx.doi.org/10.1038/s41398-017-0033-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802566/
https://www.ncbi.nlm.nih.gov/pubmed/29249828
http://dx.doi.org/10.1038/s41398-017-0033-2

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