SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia

T-cell prolymphocytic leukemia (T-PLL) is an aggressive malignancy with a median survival of the patients of less than two years. Besides characteristic chromosomal translocations, frequent mutations affect the ATM gene, JAK/STAT pathway members, and epigenetic regulators. We here performed a target...

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Detalles Bibliográficos
Autores principales: Johansson, Patricia, Klein-Hitpass, Ludger, Choidas, Axel, Habenberger, Peter, Mahboubi, Bijan, Kim, Baek, Bergmann, Anke, Scholtysik, René, Brauser, Martina, Lollies, Anna, Siebert, Reiner, Zenz, Thorsten, Dührsen, Ulrich, Küppers, Ralf, Dürig, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802577/
https://www.ncbi.nlm.nih.gov/pubmed/29352181
http://dx.doi.org/10.1038/s41408-017-0036-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802577/
https://www.ncbi.nlm.nih.gov/pubmed/29352181
http://dx.doi.org/10.1038/s41408-017-0036-5

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