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Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia
Mood instability is a core clinical feature of affective and psychotic disorders. In keeping with the Research Domain Criteria approach, it may be a useful construct for identifying biology that cuts across psychiatric categories. We aimed to investigate the biological validity of a simple measure o...
Autores principales: | Ward, Joey, Strawbridge, Rona J., Bailey, Mark E. S., Graham, Nicholas, Ferguson, Amy, Lyall, Donald M., Cullen, Breda, Pidgeon, Laura M., Cavanagh, Jonathan, Mackay, Daniel F., Pell, Jill P., O’Donovan, Michael, Escott-Price, Valentina, Smith, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802589/ https://www.ncbi.nlm.nih.gov/pubmed/29187730 http://dx.doi.org/10.1038/s41398-017-0012-7 |
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