A microengineered vascularized bleeding model that integrates the principal components of hemostasis

Hemostasis encompasses an ensemble of interactions among platelets, coagulation factors, blood cells, endothelium, and hemodynamic forces, but current assays assess only isolated aspects of this complex process. Accordingly, here we develop a comprehensive in vitro mechanical injury bleeding model c...

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Detalles Bibliográficos
Autores principales: Sakurai, Yumiko, Hardy, Elaissa T., Ahn, Byungwook, Tran, Reginald, Fay, Meredith E., Ciciliano, Jordan C., Mannino, Robert G., Myers, David R., Qiu, Yongzhi, Carden, Marcus A., Baldwin, W. Hunter, Meeks, Shannon L., Gilbert, Gary E., Jobe, Shawn M., Lam, Wilbur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802762/
https://www.ncbi.nlm.nih.gov/pubmed/29410404
http://dx.doi.org/10.1038/s41467-018-02990-x

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