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Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system

Legionella pneumophila, a causative agent of pneumonia, utilizes the Type 4B secretion (T4BS) system to translocate over 300 effectors into the host cell during infection. T4BS systems are encoded by a large gene cluster termed dot/icm, three components of which, DotL, DotM, and DotN, form the “coup...

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Detalles Bibliográficos
Autores principales: Meir, Amit, Chetrit, David, Liu, Luying, Roy, Craig R., Waksman, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802825/
https://www.ncbi.nlm.nih.gov/pubmed/29410427
http://dx.doi.org/10.1038/s41467-017-02578-x

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