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Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells

Adipose tissue is a specialized organ that synthesizes and stores fat. During adipogenesis, Rho and Rho-associated kinase (ROCK) 2 are inactivated, which enhances the expression of pro-adipogenic genes and induces the loss of actin stress fibers. Furthermore, pan ROCK inhibitors enhance adipogenesis...

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Detalles Bibliográficos
Autores principales:	Diep, Duy Trong Vien, Hong, Kyungki, Khun, Triyeng, Zheng, Mei, ul-Haq, Asad, Jun, Hee-Sook, Kim, Young-Bum, Chun, Kwang-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802830/ https://www.ncbi.nlm.nih.gov/pubmed/29410516 http://dx.doi.org/10.1038/s41598-018-20821-3

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