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RETRACTED ARTICLE: Identification of a novel Na(+)-coupled Fe(3+)-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells

NaCT is a Na(+)-coupled transporter for citrate expressed in hepatocytes and neurons. It is the mammalian ortholog of INDY (I’m Not Dead Yet), a transporter which modifies lifespan in Drosophila. Here we describe a hitherto unknown transport system for citrate in mammalian cells. When liver and mamm...

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Detalles Bibliográficos
Autores principales: Ogura, Jiro, Babu, Ellappan, Miyauchi, Seiji, Ramachandran, Sabarish, Nemeth, Elizebeta, Bhutia, Yangzom D., Ganapathy, Vadivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802838/
https://www.ncbi.nlm.nih.gov/pubmed/29410496
http://dx.doi.org/10.1038/s41598-018-20620-w