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Tissue analyses reveal a potential immune-adjuvant function of FAP-1 positive fibroblasts in non-small cell lung cancer
OBJECTIVES: Selective targeting of cancer-associated fibroblasts (CAFs) has been proposed to synergize with immune-checkpoint inhibitors. While the roles of CAFs in cancer development are well described, their immune-regulatory properties remain incompletely understood. This study investigates corre...
Autores principales: | Kilvaer, Thomas Karsten, Rakaee, Mehrdad, Hellevik, Turid, Østman, Arne, Strell, Carina, Bremnes, Roy M., Busund, Lill-Tove, Dønnem, Tom, Martinez-Zubiaurre, Inigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802915/ https://www.ncbi.nlm.nih.gov/pubmed/29415055 http://dx.doi.org/10.1371/journal.pone.0192157 |
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