Pyrazines from bacteria and ants: convergent chemistry within an ecological niche

Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified...

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Autores principales: Silva-Junior, Eduardo A., Ruzzini, Antonio C., Paludo, Camila R., Nascimento, Fabio S., Currie, Cameron R., Clardy, Jon, Pupo, Mônica T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803209/
https://www.ncbi.nlm.nih.gov/pubmed/29416082
http://dx.doi.org/10.1038/s41598-018-20953-6
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author Silva-Junior, Eduardo A.
Ruzzini, Antonio C.
Paludo, Camila R.
Nascimento, Fabio S.
Currie, Cameron R.
Clardy, Jon
Pupo, Mônica T.
author_facet Silva-Junior, Eduardo A.
Ruzzini, Antonio C.
Paludo, Camila R.
Nascimento, Fabio S.
Currie, Cameron R.
Clardy, Jon
Pupo, Mônica T.
author_sort Silva-Junior, Eduardo A.
collection PubMed
description Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified as ant trail and alarm pheromones. We found that L-threonine induces the bacterial production of the trail pheromone pyrazines, which are common for the host leaf-cutter ants. Isotope feeding experiments revealed that L-threonine along with sodium acetate were the biosynthetic precursors of these natural products and a biosynthetic pathway was proposed.
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spelling pubmed-58032092018-02-14 Pyrazines from bacteria and ants: convergent chemistry within an ecological niche Silva-Junior, Eduardo A. Ruzzini, Antonio C. Paludo, Camila R. Nascimento, Fabio S. Currie, Cameron R. Clardy, Jon Pupo, Mônica T. Sci Rep Article Ants use pheromones to coordinate their communal activity. Volatile pyrazines, for instance, mediate food resource gathering and alarm behaviors in different ant species. Here we report that leaf-cutter ant-associated bacteria produce a family of pyrazines that includes members previously identified as ant trail and alarm pheromones. We found that L-threonine induces the bacterial production of the trail pheromone pyrazines, which are common for the host leaf-cutter ants. Isotope feeding experiments revealed that L-threonine along with sodium acetate were the biosynthetic precursors of these natural products and a biosynthetic pathway was proposed. Nature Publishing Group UK 2018-02-07 /pmc/articles/PMC5803209/ /pubmed/29416082 http://dx.doi.org/10.1038/s41598-018-20953-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Silva-Junior, Eduardo A.
Ruzzini, Antonio C.
Paludo, Camila R.
Nascimento, Fabio S.
Currie, Cameron R.
Clardy, Jon
Pupo, Mônica T.
Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title_full Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title_fullStr Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title_full_unstemmed Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title_short Pyrazines from bacteria and ants: convergent chemistry within an ecological niche
title_sort pyrazines from bacteria and ants: convergent chemistry within an ecological niche
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803209/
https://www.ncbi.nlm.nih.gov/pubmed/29416082
http://dx.doi.org/10.1038/s41598-018-20953-6
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