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Nuclear FAK and its kinase activity regulate VEGFR2 transcription in angiogenesis of adult mice

Focal adhesion kinase (FAK) is essential in embryonic angiogenesis by regulating endothelial cell (EC) survival and barrier functions through its kinase-independent and –dependent activities. Here, we generated EC-specific tamoxifen-inducible FAK knockout and FAK kinase-defective (KD) mutant knockin...

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Detalles Bibliográficos
Autores principales:	Sun, Shaogang, Wu, Hsin-Jung, Guan, Jun-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803223/ https://www.ncbi.nlm.nih.gov/pubmed/29416084 http://dx.doi.org/10.1038/s41598-018-20930-z

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