Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains

In meso crystallization of membrane proteins from lipidic mesophases is central to protein structural biology but limited to membrane proteins with small extracellular domains (ECDs), comparable to the water channels (3–5 nm) of the mesophase. Here we present a strategy expanding the scope of in mes...

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Detalles Bibliográficos
Autores principales: Zabara, Alexandru, Chong, Josephine Tse Yin, Martiel, Isabelle, Stark, Laura, Cromer, Brett A., Speziale, Chiara, Drummond, Calum John, Mezzenga, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803273/
https://www.ncbi.nlm.nih.gov/pubmed/29416037
http://dx.doi.org/10.1038/s41467-018-02996-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803273/
https://www.ncbi.nlm.nih.gov/pubmed/29416037
http://dx.doi.org/10.1038/s41467-018-02996-5

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