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Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains
In meso crystallization of membrane proteins from lipidic mesophases is central to protein structural biology but limited to membrane proteins with small extracellular domains (ECDs), comparable to the water channels (3–5 nm) of the mesophase. Here we present a strategy expanding the scope of in mes...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803273/ https://www.ncbi.nlm.nih.gov/pubmed/29416037 http://dx.doi.org/10.1038/s41467-018-02996-5 |