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miR‐422a suppresses SMAD4 protein expression and promotes resistance to muscle loss

BACKGROUND: Loss of muscle mass and strength are important sequelae of chronic disease, but the response of individuals is remarkably variable, suggesting important genetic and epigenetic modulators of muscle homeostasis. Such factors are likely to modify the activity of pathways that regulate wasti...

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Detalles Bibliográficos
Autores principales: Paul, Richard, Lee, Jen, Donaldson, Anna V., Connolly, Martin, Sharif, Mohammad, Natanek, Samantha Amanda, Rosendahl, Ulrich, Polkey, Michael I., Griffiths, Mark, Kemp, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803610/
https://www.ncbi.nlm.nih.gov/pubmed/28984049
http://dx.doi.org/10.1002/jcsm.12236

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