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Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study

OBJECTIVE: Acute lymphocytic leukemia (ALL) is a rare malignant neoplasm that develops from abnormal lymphoid stem cells. ALL incidence is highest among children and declines towards adolescence. There is limited data on the epidemiology of ALL, especially in Canada. This retrospective cohort study...

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Autores principales: Snodgrass, Rayven, Nguyen, Leonard T., Guo, Maggie, Vaska, Marcus, Naugler, Christopher, Rashid-Kolvear, Fariborz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803905/
https://www.ncbi.nlm.nih.gov/pubmed/29415769
http://dx.doi.org/10.1186/s13104-018-3225-9
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author Snodgrass, Rayven
Nguyen, Leonard T.
Guo, Maggie
Vaska, Marcus
Naugler, Christopher
Rashid-Kolvear, Fariborz
author_facet Snodgrass, Rayven
Nguyen, Leonard T.
Guo, Maggie
Vaska, Marcus
Naugler, Christopher
Rashid-Kolvear, Fariborz
author_sort Snodgrass, Rayven
collection PubMed
description OBJECTIVE: Acute lymphocytic leukemia (ALL) is a rare malignant neoplasm that develops from abnormal lymphoid stem cells. ALL incidence is highest among children and declines towards adolescence. There is limited data on the epidemiology of ALL, especially in Canada. This retrospective cohort study used patient data from the Calgary Laboratory Services Cancer Cytogenetics Laboratory to report the incidence rate of ALL in Calgary, Alberta, Canada. New cases of ALL were identified for the 5-year period of January 1, 2011 until December 31, 2015. Reported incidence rates were categorized by sex and age groups, and age-standardized to the Canadian population. RESULTS: There were an average of 11.4 new cases of ALL diagnosed per year between 2011 and 2015. The total incidence rate per 100,000 person-years was 0.84. Incidence rates peaked in children aged 0–4 with 7.55 and 3.32 cases per 100,000 person-years for males and females, respectively. The median age of diagnosis was 8 years. Incidence rates were generally lowest for adults aged 20 and over. The ratio of males to females diagnosed with ALL was 1.59. Overall, the recent incidence of ALL in Calgary is comparatively low with a preference for males and children below 5 years of age.
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spelling pubmed-58039052018-02-14 Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study Snodgrass, Rayven Nguyen, Leonard T. Guo, Maggie Vaska, Marcus Naugler, Christopher Rashid-Kolvear, Fariborz BMC Res Notes Research Note OBJECTIVE: Acute lymphocytic leukemia (ALL) is a rare malignant neoplasm that develops from abnormal lymphoid stem cells. ALL incidence is highest among children and declines towards adolescence. There is limited data on the epidemiology of ALL, especially in Canada. This retrospective cohort study used patient data from the Calgary Laboratory Services Cancer Cytogenetics Laboratory to report the incidence rate of ALL in Calgary, Alberta, Canada. New cases of ALL were identified for the 5-year period of January 1, 2011 until December 31, 2015. Reported incidence rates were categorized by sex and age groups, and age-standardized to the Canadian population. RESULTS: There were an average of 11.4 new cases of ALL diagnosed per year between 2011 and 2015. The total incidence rate per 100,000 person-years was 0.84. Incidence rates peaked in children aged 0–4 with 7.55 and 3.32 cases per 100,000 person-years for males and females, respectively. The median age of diagnosis was 8 years. Incidence rates were generally lowest for adults aged 20 and over. The ratio of males to females diagnosed with ALL was 1.59. Overall, the recent incidence of ALL in Calgary is comparatively low with a preference for males and children below 5 years of age. BioMed Central 2018-02-07 /pmc/articles/PMC5803905/ /pubmed/29415769 http://dx.doi.org/10.1186/s13104-018-3225-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Snodgrass, Rayven
Nguyen, Leonard T.
Guo, Maggie
Vaska, Marcus
Naugler, Christopher
Rashid-Kolvear, Fariborz
Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title_full Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title_fullStr Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title_full_unstemmed Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title_short Incidence of acute lymphocytic leukemia in Calgary, Alberta, Canada: a retrospective cohort study
title_sort incidence of acute lymphocytic leukemia in calgary, alberta, canada: a retrospective cohort study
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803905/
https://www.ncbi.nlm.nih.gov/pubmed/29415769
http://dx.doi.org/10.1186/s13104-018-3225-9
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