Evidence for a pre-malignant cell line in a skin biopsy from a patient with Nijmegen breakage syndrome

BACKGROUND: Nijmegen breakage syndrome is an autosomal recessive disorder characterized by microcephaly, immunodeficiency, hypersensitivity to X-irradiation, and a high predisposition to cancer. Nibrin, the product of the NBN gene, is part of the MRE11/RAD50 (MRN) complex that is involved in the rep...

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Detalles Bibliográficos
Autores principales: Habib, Raneem, Neitzel, Heidemarie, Ernst, Aurelie, Wong, John K. L., Goryluk-Kozakiewicz, Bozenna, Gerlach, Antje, Demuth, Ilja, Sperling, Karl, Chrzanowska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803995/
https://www.ncbi.nlm.nih.gov/pubmed/29445421
http://dx.doi.org/10.1186/s13039-018-0364-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803995/
https://www.ncbi.nlm.nih.gov/pubmed/29445421
http://dx.doi.org/10.1186/s13039-018-0364-6

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