Cargando…

Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma

BACKGROUND: Polycomb repressive complex 2 (PRC2; formed by EZH2, SUZ12, and EED protein subunits) and PRC1 (BMI1 protein) induce gene silencing through histone modification by H3K27me3. In the present study, we characterized the PRC expression pattern and its clinical implication in sarcoma. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cho, Yong Jin, Kim, Soo Hee, Kim, Eun Kyung, Han, Jung Woo, Shin, Kyoo-Ho, Hu, Hyuk, Kim, Kyung Sik, Choi, Young Deuk, Kim, Sunghoon, Lee, Young Han, Suh, Jin-Suck, Ahn, Joong Bae, Chung, Hyun Cheol, Noh, Sung Hoon, Rha, Sun Young, Jung, Sung-Taek, Kim, Hyo Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804074/ https://www.ncbi.nlm.nih.gov/pubmed/29415665 http://dx.doi.org/10.1186/s12885-018-4066-6

Ejemplares similares

Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders
por: Tomassi, Stefano, et al.
Publicado: (2021)

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma
por: Kim, Joo Hoon, et al.
Publicado: (2016)

Prognostic implications of PD-L1 expression in patients with soft tissue sarcoma
por: Kim, Chan, et al.
Publicado: (2016)

Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer
por: Kim, Woojin, et al.
Publicado: (2013)

The Central Role of EED in the Orchestration of Polycomb Group Complexes
por: Cao, Qi, et al.
Publicado: (2014)

Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer
por: Benard, Anne, et al.
Publicado: (2014)

Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms
por: Brecqueville, M, et al.
Publicado: (2011)

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors
por: Lee, William, et al.
Publicado: (2014)

Prognostic Model to Predict Survival Outcome for Curatively Resected Liposarcoma: A Multi-Institutional Experience
por: Oh, Yoon Jung, et al.
Publicado: (2016)

The Polycomb Group Protein EED Is Dispensable for the Initiation of Random X-Chromosome Inactivation
por: Kalantry, Sundeep, et al.
Publicado: (2006)

Polycomb Protein Eed is Required for Neurogenesis and Cortical Injury Activation in the Subventricular Zone
por: Sun, Bin, et al.
Publicado: (2018)

Gene silencing in HIV-1 latency by polycomb repressive group
por: Kim, Hyeon Guk, et al.
Publicado: (2011)

Human Polycomb group EED protein negatively affects HIV-1 assembly and release
por: Rakotobe, Dina, et al.
Publicado: (2007)

Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis
por: Yu, Wenhua, et al.
Publicado: (2017)

Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator
por: Kim, Jung, et al.
Publicado: (2018)

The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation
por: Kalantry, Sundeep, et al.
Publicado: (2006)

Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed
por: Alexander, Mary Kate, et al.
Publicado: (2007)

Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer
por: Li, Xin, et al.
Publicado: (2021)

Polycomb group protein Suz12 is regulated by a novel miRNA-like small RNA
por: Penfornis, Patrice, et al.
Publicado: (2018)

Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
por: Li, Ling, et al.
Publicado: (2017)

Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus
por: Liu, Pei-Pei, et al.
Publicado: (2019)

Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer
por: Chen, Huiming, et al.
Publicado: (2015)

Inhibition of polycomb repressive complex 2 by targeting EED protects against cisplatin‐induced acute kidney injury
por: Yu, Chao, et al.
Publicado: (2022)

Magnetic Resonance Arthrographic Dissection of Posterolateral Corner of the Knee: Revealing the Meniscofibular Ligament
por: Lee, Young Han, et al.
Publicado: (2012)

Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency
por: Ikeda, Kenichiro, et al.
Publicado: (2016)

Incidental detection of pancreatic hemangioma mimicking a metastatic tumor of renal cell carcinoma
por: Kim, Sung Hyun, et al.
Publicado: (2016)

Repeat Targeted Prostate Biopsy under Guidance of Multiparametric MRI-Correlated Real-Time Contrast-Enhanced Ultrasound for Patients with Previous Negative Biopsy and Elevated Prostate-Specific Antigen: A Prospective Study
por: Jang, Dong Ryul, et al.
Publicado: (2015)

The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens
por: Steele, J C, et al.
Publicado: (2006)

High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer
por: Jang, Si-Hyong, et al.
Publicado: (2016)

Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein
por: Kim, Kyung Rok, et al.
Publicado: (2020)

A comparison of the analysis of 3 types of body fluids using the XN-350 hematology analyzer versus light microscopy assessment
por: Lee, Jiwon, et al.
Publicado: (2021)

P1498: INHIBITION OF POLYCOMB REPRESSIVE COMPLEX 2 THROUGH EED INDUCES FETAL HEMOGLOBIN IN HEALTHY AND SICKLE CELL DISEASE MODELS
por: Stuart, B., et al.
Publicado: (2022)

Accuracy of periodontal probe visibility in the assessment of gingival thickness
por: Kim, Young-Sung, et al.
Publicado: (2020)

HbA1c changes in patients with diabetes following periodontal therapy
por: Kim, Su-Hwan, et al.
Publicado: (2021)

Schedule-Dependent Effect of Epigallocatechin-3-Gallate (EGCG) with Paclitaxel on H460 Cells
por: Park, Sunghoon, et al.
Publicado: (2014)

Outcomes of pediatric acute myeloid leukemia patients with FLT3-ITD mutations in the pre-FLT3 inhibitor era
por: Choi, Sujin, et al.
Publicado: (2020)

Going beyond Polycomb: EZH2 Functions in Prostate Cancer
por: Park, Su H., et al.
Publicado: (2021)

DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAs
por: So, Ah-Young, et al.
Publicado: (2011)

Polycomb-Mediated Gene Silencing in Arabidopsis thaliana
por: Kim, Dong-Hwan, et al.
Publicado: (2014)

pT3 Predictive Factors in Patients with a Gleason Score of 6 in Prostate Biopsies
por: Kim, Sung Jin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0l3dfdur056rjt740pcksund3r