Pharmacologic Reprogramming Designed to Induce a Warburg Effect in Porcine Fetal Fibroblasts Alters Gene Expression and Quantities of Metabolites from Conditioned Media Without Increased Cell Proliferation

The Warburg effect is a metabolic phenomenon characterized by increased glycolytic activity, decreased mitochondrial oxidative phosphorylation, and the production of lactate. This metabolic phenotype is characterized in rapidly proliferative cell types such as cancerous cells and embryonic stem cell...

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Detalles Bibliográficos
Autores principales: Mordhorst, Bethany R., Murphy, Stephanie L., Ross, Renee M., Samuel, Melissa S., Salazar, Shirley Rojas, Ji, Tieming, Behura, Susanta K., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804098/
https://www.ncbi.nlm.nih.gov/pubmed/29412741
http://dx.doi.org/10.1089/cell.2017.0040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804098/
https://www.ncbi.nlm.nih.gov/pubmed/29412741
http://dx.doi.org/10.1089/cell.2017.0040

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