Cargando…

Wushenziye Formula Improves Skeletal Muscle Insulin Resistance in Type 2 Diabetes Mellitus via PTP1B-IRS1-Akt-GLUT4 Signaling Pathway

Background. Wushenziye formula (WSZYF) is an effective traditional Chinese medicine in the treatment of type 2 diabetes mellitus (T2DM). Aim. This study aimed to identify the effects and underlying mechanisms of WSZYF on improving skeletal muscle insulin resistance in T2DM. Methods. An animal model...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Chunyu, Chang, Hong, La, Xiaojin, Li, Ji-an
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804399/ https://www.ncbi.nlm.nih.gov/pubmed/29479370 http://dx.doi.org/10.1155/2017/4393529

Ejemplares similares

Wushenziye Formula Inhibits Pancreatic β Cell Apoptosis in Type 2 Diabetes Mellitus via MEK-ERK-Caspase-3 Signaling Pathway
por: Tian, Chunyu, et al.
Publicado: (2018)

Stevioside Attenuates Insulin Resistance in Skeletal Muscle by Facilitating IR/IRS-1/Akt/GLUT 4 Signaling Pathways: An In Vivo and In Silico Approach
por: Deenadayalan, Abilasha, et al.
Publicado: (2021)

Panax notoginseng saponins alleviate skeletal muscle insulin resistance by regulating the IRS1–PI3K–AKT signaling pathway and GLUT4 expression
por: Guo, Xuan, et al.
Publicado: (2019)

Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice
por: González-Rodríguez, Águeda, et al.
Publicado: (2010)

A Novel PTP1B Inhibitor-Phosphate of Polymannuronic Acid Ameliorates Insulin Resistance by Regulating IRS-1/Akt Signaling
por: Li, Dan, et al.
Publicado: (2021)

Effects of Modified Sanzi Yangqin Decoction on Tyrosine Phosphorylation of IRS-1 in Skeletal Muscle of Type 2 Diabetic Rats
por: Wang, Ya, et al.
Publicado: (2018)

A steady state analysis indicates that negative feedback regulation of PTP1B by Akt elicits bistability in insulin-stimulated GLUT4 translocation
por: Giri, Lopamudra, et al.
Publicado: (2004)

WNK1 kinase is essential for insulin‐stimulated GLUT4 trafficking in skeletal muscle
por: Kim, Ji‐Hee, et al.
Publicado: (2018)

Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice
por: Ye, Zimengwei, et al.
Publicado: (2022)

ATM and GLUT1-S490 Phosphorylation Regulate GLUT1 Mediated Transport in Skeletal Muscle
por: Andrisse, Stanley, et al.
Publicado: (2013)

Simiao Wan and its ingredients alleviate type 2 diabetes mellitus via IRS1/AKT2/FOXO1/GLUT2 signaling
por: Xia, Ting, et al.
Publicado: (2023)

Increasing effect of Tangzhiqing formula on IRS-1-dependent PI3K/AKT signaling in muscle
por: Gao, Jing, et al.
Publicado: (2014)

Oleuropein improves insulin resistance in skeletal muscle by promoting the translocation of GLUT4
por: Fujiwara, Yoko, et al.
Publicado: (2017)

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle
por: Knudsen, Jonas R, et al.
Publicado: (2023)

Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity
por: Song, Shanshan, et al.
Publicado: (2021)

Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
por: Beg, Muheeb, et al.
Publicado: (2017)

Sanghuang Tongxie Formula Ameliorates Insulin Resistance in Drosophila Through Regulating PI3K/Akt Signaling
por: Cao, Xuqing, et al.
Publicado: (2022)

Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway
por: Miao, Miao, et al.
Publicado: (2021)

MicroRNAs-Mediated Regulation of Skeletal Muscle GLUT4 Expression and Translocation in Insulin Resistance
por: Esteves, João Victor, et al.
Publicado: (2017)

The effect of cassia seed extract on the regulation of the LKB1–AMPK–GLUT4 signaling pathway in the skeletal muscle of diabetic rats to improve the insulin sensitivity of the skeletal muscle
por: Wang, Qiu-Ying, et al.
Publicado: (2019)

Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice
por: Ji, Wenjun, et al.
Publicado: (2014)

Insulin-induced Effects on the Subcellular Localization of AKT1, AKT2 and AS160 in Rat Skeletal Muscle
por: Zheng, Xiaohua, et al.
Publicado: (2016)

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
por: Morino, Katsutaro, et al.
Publicado: (2008)

Placental expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in pregnancies complicated by gestational and type 1 diabetes mellitus
por: Stanirowski, Paweł Jan, et al.
Publicado: (2021)

A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway
por: Liu, Yaqian, et al.
Publicado: (2017)

Trilobatin ameliorates insulin resistance through IRS-AKT-GLUT4 signaling pathway in C2C12 myotubes and ob/ob mice
por: Liu, Min, et al.
Publicado: (2020)

Data on the expression and insulin-stimulated phosphorylation of IRS-1 by miR-96 in L6-GLUT4myc myocytes
por: Yang, Won-Mo, et al.
Publicado: (2017)

Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle
por: Karlsson, Håkan K.R., et al.
Publicado: (2009)

Effect of berberine on the HPA-axis pathway and skeletal muscle GLUT4 in type 2 diabetes mellitus rats
por: Mi, Jia, et al.
Publicado: (2019)

Analysis of GLUT4 Distribution in Whole Skeletal Muscle Fibers: Identification of Distinct Storage Compartments That Are Recruited by Insulin and Muscle Contractions
por: Ploug, Thorkil, et al.
Publicado: (1998)

Advanced glycation end products-induced insulin resistance involves repression of skeletal muscle GLUT4 expression
por: Pinto-Junior, Danilo C., et al.
Publicado: (2018)

Amelioration of High-Insulin-Induced Skeletal Muscle Cell Insulin Resistance by Resveratrol Is Linked to Activation of AMPK and Restoration of GLUT4 Translocation
por: Vlavcheski, Filip, et al.
Publicado: (2020)

Activation of the NLRP3 Inflammasome Increases the IL-1β Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance
por: Américo-Da-Silva, Luan, et al.
Publicado: (2021)

MFGE8 inhibits insulin signaling through PTP1B
por: Datta, Ritwik, et al.
Publicado: (2023)

Effects of four weeks intermittent hypoxia intervention on glucose homeostasis, insulin sensitivity, GLUT4 translocation, insulin receptor phosphorylation, and Akt activity in skeletal muscle of obese mice with type 2 diabetes
por: Wang, Yun, et al.
Publicado: (2018)

Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle
Publicado: (1996)

Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance in vitro and in vivo
por: Yao, Xinlei, et al.
Publicado: (2023)

Mulberry (Morus alba L.) Leaf Extract and 1-Deoxynojirimycin Improve Skeletal Muscle Insulin Resistance via the Activation of IRS-1/PI3K/Akt Pathway in db/db Mice
por: Kang, Chae-Won, et al.
Publicado: (2022)

H19 inhibition increases HDAC6 and regulates IRS1 levels and insulin signaling in the skeletal muscle during diabetes
por: Kumar, Amit, et al.
Publicado: (2022)

Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake
por: McMillin, Shawna L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t6thgac3kj7cuum2arnnbe98o9