Cargando…

Exemestane Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells and Promoting the Secretion of Interleukin 10

Exemestane (EXE) is an irreversible steroidal aromatase inhibitor mainly used as an adjuvant endocrine therapy for postmenopausal women suffering from breast cancer. Besides inhibiting aromatase activity, EXE has multiple biological functions, such as antiproliferation, anti-inflammatory, and antiox...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ya-Hui, Li, Rong-Kun, Fu, Ying, Li, Jun, Yang, Xiao-Mei, Zhang, Yan-Li, Zhu, Lei, Yang, Qin, Gu, Jian-Ren, Xing, Xin, Zhang, Zhi-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804406/ https://www.ncbi.nlm.nih.gov/pubmed/29464186 http://dx.doi.org/10.1155/2017/3072745

Ejemplares similares

Bevacizumab Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells
por: Huang, Yangqing, et al.
Publicado: (2013)

Fuzheng Huayu Capsule Attenuates Hepatic Fibrosis by Inhibiting Activation of Hepatic Stellate Cells
por: Wu, Mei, et al.
Publicado: (2020)

Hydrodynamics-based transfection of rat interleukin-10 gene attenuates porcine serum-induced liver fibrosis in rats by inhibiting the activation of hepatic stellate cells
por: HUANG, YUE-HONG, et al.
Publicado: (2014)

Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway
por: Liang, Lei, et al.
Publicado: (2016)

Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells
por: Zhang, Feng, et al.
Publicado: (2014)

Tetrahydropalmatine attenuates liver fibrosis by suppressing endoplasmic reticulum stress in hepatic stellate cells
por: Xuan, Yuanyuan, et al.
Publicado: (2022)

Targeted delivery of hyaluronic acid nanomicelles to hepatic stellate cells in hepatic fibrosis rats
por: Li, Wenhao, et al.
Publicado: (2020)

Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis
por: Pu, Shiyun, et al.
Publicado: (2021)

Hepatic stellate cells specific liposomes with the Toll‐like receptor 4 shRNA attenuates liver fibrosis
por: Zhang, Yuwei, et al.
Publicado: (2020)

Osthole ameliorates hepatic fibrosis and inhibits hepatic stellate cell activation
por: Liu, Ya-Wei, et al.
Publicado: (2015)

Germacrone Attenuates Hepatic Stellate Cells Activation and Liver Fibrosis via Regulating Multiple Signaling Pathways
por: Li, Zhiyong, et al.
Publicado: (2021)

Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells
por: Chen, Ling, et al.
Publicado: (2015)

Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis
por: Yin, Xiaochun, et al.
Publicado: (2022)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
por: Knorr, Jana, et al.
Publicado: (2023)

Gypenosides Synergistically Reduce the Extracellular Matrix of Hepatic Stellate Cells and Ameliorate Hepatic Fibrosis in Mice
por: Li, Han, et al.
Publicado: (2023)

Hepatic stellate cells and parasite-induced liver fibrosis
por: Anthony, Barrie, et al.
Publicado: (2010)

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis
por: Schon, Hans-Theo, et al.
Publicado: (2016)

Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets
por: Zhang, Chong-Yang, et al.
Publicado: (2016)

Herbal compound “Songyou Yin” attenuates hepatoma cell invasiveness and metastasis through downregulation of cytokines secreted by activated hepatic stellate cells
por: Jia, Qing-An, et al.
Publicado: (2013)

Hepatic Stellate Cells Secreted Hepatocyte Growth Factor Contributes to the Chemoresistance of Hepatocellular Carcinoma
por: Yu, Guofeng, et al.
Publicado: (2013)

Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells
por: Feng, Yi, et al.
Publicado: (2016)

Clusterin Attenuates Hepatic Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Downregulating the Smad3 Signaling Pathway
por: Seo, Hye-Young, et al.
Publicado: (2019)

GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation
por: Zhang, Haoye, et al.
Publicado: (2022)

EZH2‐mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis
por: Yang, Yang, et al.
Publicado: (2017)

Ivermectin Attenuates CCl(4)-Induced Liver Fibrosis in Mice by Suppressing Hepatic Stellate Cell Activation
por: Ying, Hanglu, et al.
Publicado: (2022)

Disulfiram inhibits liver fibrosis in rats by suppressing hepatic stellate cell activation and viability
por: Yang, Xiao-Mei, et al.
Publicado: (2022)

Crosstalk between NK cells and hepatic stellate cells in liver fibrosis
por: Zhang, Yang, et al.
Publicado: (2022)

Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis
por: Li, Zhiman, et al.
Publicado: (2021)

Mechanical homeostasis imbalance in hepatic stellate cells activation and hepatic fibrosis
por: Zhao, Yuan-Quan, et al.
Publicado: (2023)

SNS-032 attenuates liver fibrosis by anti-active hepatic stellate cells via inhibition of cyclin dependent kinase 9
por: He, Xiao-Li, et al.
Publicado: (2022)

Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice
por: Zhao, Lei, et al.
Publicado: (2023)

The C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis
por: Zhang, Mengfan, et al.
Publicado: (2023)

Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways
por: Peng, Yu, et al.
Publicado: (2019)

Adenovirus-mediated knockdown of activin A receptor type 2A attenuates immune-induced hepatic fibrosis in mice and inhibits interleukin-17-induced activation of primary hepatic stellate cells
por: Zhang, Hongjun, et al.
Publicado: (2018)

Targeted Drug Delivery to Hepatic Stellate Cells for the Treatment of Liver Fibrosis
por: Chen, Zhijin, et al.
Publicado: (2019)

11β-hydroxysteroid dehydrogenase-1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis
por: Xiao, Wei, et al.
Publicado: (2020)

Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells
por: Park, Yong Joo, et al.
Publicado: (2020)

Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis
por: Khomich, Olga, et al.
Publicado: (2019)

MicroRNA-98 Inhibits Hepatic Stellate Cell Activation and Attenuates Liver Fibrosis by Regulating HLF Expression
por: Wang, Qi, et al.
Publicado: (2020)

Roles of hepatic stellate cells in NAFLD: From the perspective of inflammation and fibrosis
por: Wang, Man, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pj90is5cbr4gdurt05e2c940om