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Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital

Background: Pulmonary embolism (PE) is a common disease in the USA responsible for up to 10% of hospital mortality. Modified wells score (MWS) and D-dimer assay are used to categorize patients into high or low probability of PE. Patient with high probability need Computed tomography pulmonary angiog...

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Autores principales: Osman, Mohammed, Subedi, Suresh Kumar, Ahmed, Azza, Khan, Jahangir, Dawood, Thair, Ríos-Bedoya, Carlos F., Bachuwa, Ghassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804676/
https://www.ncbi.nlm.nih.gov/pubmed/29441158
http://dx.doi.org/10.1080/20009666.2018.1428024
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author Osman, Mohammed
Subedi, Suresh Kumar
Ahmed, Azza
Khan, Jahangir
Dawood, Thair
Ríos-Bedoya, Carlos F.
Bachuwa, Ghassan
author_facet Osman, Mohammed
Subedi, Suresh Kumar
Ahmed, Azza
Khan, Jahangir
Dawood, Thair
Ríos-Bedoya, Carlos F.
Bachuwa, Ghassan
author_sort Osman, Mohammed
collection PubMed
description Background: Pulmonary embolism (PE) is a common disease in the USA responsible for up to 10% of hospital mortality. Modified wells score (MWS) and D-dimer assay are used to categorize patients into high or low probability of PE. Patient with high probability need Computed tomography pulmonary angiography (CTPA), while patients with low probability and low D-dimer can safely forgo the CTPA. Objectives: The aim of this study was to investigate the rate of inappropriate CTPA use in the emergency department of a community teaching hospital. Methods: A retrospective chart review of adult patients who underwent CTPA for suspected PE in the emergency department for 2015 was done. CTPA use was considered inappropriate if MWS was less than or equal to 4 and D-dimer was either not ordered or its value was less than 500 μg/L. Bivariate analysis with Fisher’s exact tests and Student’s t-tests as well as multivariate logistic regression analysis were done to examine relationship between study explanatory variables and study outcome. Results: 295 patients were included in the study. The mean age was 51.2(±14.5) years, 68.8% were females. The prevalence of PE was 5.4% and 41% of the CTPAs -were inappropriately ordered. Males were twice (OR 2.1; 95% CI 1.2, 3.6) as likely as females to have an inappropriately ordered CTPA after controlling for a high MWS, age, and tobacco history. Conclusion: CTPA is overused to diagnose PE in the emergency department. Quality improvement projects are needed to encourage physicians to adhere to the current guidelines.
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spelling pubmed-58046762018-02-13 Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital Osman, Mohammed Subedi, Suresh Kumar Ahmed, Azza Khan, Jahangir Dawood, Thair Ríos-Bedoya, Carlos F. Bachuwa, Ghassan J Community Hosp Intern Med Perspect Research Article Background: Pulmonary embolism (PE) is a common disease in the USA responsible for up to 10% of hospital mortality. Modified wells score (MWS) and D-dimer assay are used to categorize patients into high or low probability of PE. Patient with high probability need Computed tomography pulmonary angiography (CTPA), while patients with low probability and low D-dimer can safely forgo the CTPA. Objectives: The aim of this study was to investigate the rate of inappropriate CTPA use in the emergency department of a community teaching hospital. Methods: A retrospective chart review of adult patients who underwent CTPA for suspected PE in the emergency department for 2015 was done. CTPA use was considered inappropriate if MWS was less than or equal to 4 and D-dimer was either not ordered or its value was less than 500 μg/L. Bivariate analysis with Fisher’s exact tests and Student’s t-tests as well as multivariate logistic regression analysis were done to examine relationship between study explanatory variables and study outcome. Results: 295 patients were included in the study. The mean age was 51.2(±14.5) years, 68.8% were females. The prevalence of PE was 5.4% and 41% of the CTPAs -were inappropriately ordered. Males were twice (OR 2.1; 95% CI 1.2, 3.6) as likely as females to have an inappropriately ordered CTPA after controlling for a high MWS, age, and tobacco history. Conclusion: CTPA is overused to diagnose PE in the emergency department. Quality improvement projects are needed to encourage physicians to adhere to the current guidelines. Taylor & Francis 2018-02-06 /pmc/articles/PMC5804676/ /pubmed/29441158 http://dx.doi.org/10.1080/20009666.2018.1428024 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Osman, Mohammed
Subedi, Suresh Kumar
Ahmed, Azza
Khan, Jahangir
Dawood, Thair
Ríos-Bedoya, Carlos F.
Bachuwa, Ghassan
Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title_full Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title_fullStr Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title_full_unstemmed Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title_short Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
title_sort computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804676/
https://www.ncbi.nlm.nih.gov/pubmed/29441158
http://dx.doi.org/10.1080/20009666.2018.1428024
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