Ontogeny-related pharmacogene changes in the pediatric liver transcriptome

OBJECTIVES: The majority of drug dosing studies are based on adult populations, with modification of the dosing for children based on size and weight. This rudimentary approach for drug dosing children is limited, as biologically a child can differ from an adult in far more aspects than just size an...

Descripción completa

Detalles Bibliográficos
Autores principales: Meier, Richard, Bi, Chengpeng, Gaedigk, Roger, Heruth, Daniel P., Ye, Shui Qing, Leeder, J. Steven, Fridley, Brooke L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805126/
https://www.ncbi.nlm.nih.gov/pubmed/29360682
http://dx.doi.org/10.1097/FPC.0000000000000326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805126/
https://www.ncbi.nlm.nih.gov/pubmed/29360682
http://dx.doi.org/10.1097/FPC.0000000000000326

Ejemplares similares