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Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes

Virus reprogramming of cellular metabolism is recognised as a critical determinant for viral growth. While most viruses appear to activate central energy metabolism, different viruses have been shown to rely on alternative mechanisms of metabolic activation. Whether related viruses exploit conserved...

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Detalles Bibliográficos
Autores principales: Mazzon, Michela, Castro, Cecilia, Thaa, Bastian, Liu, Lifeng, Mutso, Margit, Liu, Xiang, Mahalingam, Suresh, Griffin, Julian L., Marsh, Mark, McInerney, Gerald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805360/
https://www.ncbi.nlm.nih.gov/pubmed/29377936
http://dx.doi.org/10.1371/journal.ppat.1006835