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SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line

Pancreatic Ductal Adenocarcinoma (PDA) has a mortality rate that nearly matches its incidence rate. Transforming Growth Factor Beta (TGF-β) is a cytokine with a dual role in tumor development switching from a tumor suppressor to a tumor promoter. There is limited knowledge of how TGF-β function swit...

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Detalles Bibliográficos
Autores principales:	Grover, Priyanka, Nath, Sritama, Nye, Monica D., Zhou, Ru, Ahmad, Mohammad, Mukherjee, Pinku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805524/ https://www.ncbi.nlm.nih.gov/pubmed/29467938 http://dx.doi.org/10.18632/oncotarget.23966

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