Metformin inhibits TGF-β1-induced epithelial-to-mesenchymal transition-like process and stem-like properties in GBM via AKT/mTOR/ZEB1 pathway

Glioblastoma (GBM) is the most frequent and aggressive brain tumor in adults. In spite of advances in diagnosis and therapy, the prognosis is still relatively poor. The invasive property of GBM is the major cause of death in patients. Epithelial-to-mesenchymal transition-like process (EMT-like proce...

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Detalles Bibliográficos
Autores principales: Song, Yang, Chen, Yong, Li, Yunqian, Lyu, Xiaoyan, Cui, Jiayue, Cheng, Ye, Zhao, Liyan, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805533/
https://www.ncbi.nlm.nih.gov/pubmed/29467947
http://dx.doi.org/10.18632/oncotarget.23317

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