Cargando…

Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system

Radioactive-iodine (RAI) therapy is typically unprevailing as anaplastic thyroid cancer (ATC) management, owing to the decrease in the endogenous sodium iodide symporter (NIS) expression. Therefore, new strategies for NIS re-induction are required to improve the efficacy of RAI therapy in ATC. In th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oh, Ji Min, Kalimuthu, Senthilkumar, Gangadaran, Prakash, Baek, Se Hwan, Zhu, Liya, Lee, Ho Won, Rajendran, Ramya Lakshmi, Hong, Chae Moon, Jeong, Shin Young, Lee, Sang-Woo, Lee, Jaetae, Ahn, Byeong-Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805537/ https://www.ncbi.nlm.nih.gov/pubmed/29467951 http://dx.doi.org/10.18632/oncotarget.24159

Ejemplares similares

Extracellular Vesicles Act as Nano-Transporters of Tyrosine Kinase Inhibitors to Revert Iodine Avidity in Thyroid Cancer
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2021)

Targeting GLI1 Transcription Factor for Restoring Iodine Avidity with Redifferentiation in Radioactive-Iodine Refractory Thyroid Cancers
por: Oh, Ji Min, et al.
Publicado: (2022)

Fluoride Exposure Induces Inhibition of Sodium/Iodide Symporter (NIS) Contributing to Impaired Iodine Absorption and Iodine Deficiency: Molecular Mechanisms of Inhibition and Implications for Public Health
por: Waugh, Declan Timothy
Publicado: (2019)

Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS
por: Oh, Ji Min, et al.
Publicado: (2021)

Mechanisms of Sodium/Iodide Symporter-Mediated Mammary Gland Iodine Compensation during Lactation
por: Fu, Min, et al.
Publicado: (2022)

Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer
por: Micali, Salvatore, et al.
Publicado: (2014)

The Sodium Iodide Symporter (NIS) as an Imaging Reporter for Gene, Viral, and Cell-based Therapies
por: Penheiter, Alan R, et al.
Publicado: (2012)

Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake
por: Chung, Taemoon, et al.
Publicado: (2015)

Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes
por: Spellerberg, Rebekka, et al.
Publicado: (2021)

Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter
por: Kaneda-Nakashima, Kazuko, et al.
Publicado: (2022)

The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue
por: Ryan, James, et al.
Publicado: (2011)

Induction of Sodium/Iodide Symporter (NIS) Expression and Radioiodine Uptake in Non-Thyroid Cancer Cells
por: Liu, Zhi, et al.
Publicado: (2012)

Effect of thyroid statuses on sodium/iodide symporter (NIS) gene expression in the extrathyroidal tissues in mice
por: Harun-Or-Rashid, et al.
Publicado: (2010)

Development of an athyroid mouse model using (131)I ablation after preparation with a low-iodine diet
por: Oh, Ji Min, et al.
Publicado: (2017)

The G395R Mutation of the Sodium/Iodide Symporter (NIS) Gene in Patients with Dyshormonogenetic Congenital Hypothyroidism
por: Mostofizade, Neda, et al.
Publicado: (2013)

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
por: Schmohl, Kathrin A., et al.
Publicado: (2017)

Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS)
por: Concilio, Susanna C., et al.
Publicado: (2020)

Codon-optimized Human Sodium Iodide Symporter (opt-hNIS) as a Sensitive Reporter and Efficient Therapeutic Gene
por: Kim, Young-Hwa, et al.
Publicado: (2015)

A novel strategy of transferring NIS protein to cells using extracellular vesicles leads to increase in iodine uptake and cytotoxicity
por: Son, Seung Hyun, et al.
Publicado: (2019)

A Probasin Promoter, Conditionally Replicating Adenovirus that Expresses the Sodium Iodide Symporter (NIS) for Radiovirotherapy of Prostate Cancer
por: Trujillo, Miguel A., et al.
Publicado: (2010)

The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells
por: Guerrieri, F, et al.
Publicado: (2013)

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(−) symporter (NIS) knockout mice
por: Ferrandino, Giuseppe, et al.
Publicado: (2017)

Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation
por: Kelkar, Madhura G., et al.
Publicado: (2016)

A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer
por: Trujillo, Miguel A., et al.
Publicado: (2012)

On the Administration of Iodine versus Iodide of Potassium
por: Dougall, John
Publicado: (1878)

Dimerization of the Sodium/Iodide Symporter
por: Thompson, Rebecca J., et al.
Publicado: (2019)

Taking Advantage of the TGFB1 Biology in Differentiated Thyroid Cancer to Stimulate Sodium Iodide Symporter (NIS)-Mediated Iodide Uptake in Engineered Mesenchymal Stem Cells
por: Han, Yang, et al.
Publicado: (2021)

The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy
por: Kitzberger, Carolin, et al.
Publicado: (2022)

Transcription Factor CREB3L1 Regulates the Expression of the Sodium/Iodide Symporter (NIS) in Rat Thyroid Follicular Cells
por: Di Giusto, Pablo, et al.
Publicado: (2022)

Evolution and developmental expression of the sodium–iodide symporter ( NIS , slc5a5) gene family: Implications for perchlorate toxicology
por: Petersen, Ann M., et al.
Publicado: (2022)

Synthesis of Aryl Iodides from Arylhydrazines and Iodine
por: Dong, Chun-ping, et al.
Publicado: (2018)

Autoinhibition by Iodide Ion in the Methionine–Iodine Reaction
por: Xu, Li, et al.
Publicado: (2020)

Action of Iodine and Iodide of Potassium on the Nervous System
Publicado: (1865)

HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy
por: Li, H, et al.
Publicado: (2013)

OR14-05 Taking Advantage Of The Interleukin-6-Biology In Differentiated Thyroid Cancer To Stimulate Sodium Iodide Symporter (NIS)-mediated Iodide Uptake In Engineered Mesenchymal Stem Cells
por: Florentine Koehler, Viktoria, et al.
Publicado: (2023)

Overexpression of Both Human Sodium Iodide Symporter (NIS) and BRG1-Bromodomain Synergistically Enhances Radioiodine Sensitivity by Stabilizing p53 through NPM1 Expression
por: Na, Juri, et al.
Publicado: (2023)

The master role of polarized NIS expression in regulating iodine metabolism in the human body
por: Lévay, Bernadett, et al.
Publicado: (2023)

Enhancement of Natural Killer Cell Cytotoxicity by Sodium/Iodide Symporter Gene-Mediated Radioiodine Pretreatment in Breast Cancer Cells
por: Kim, Hae Won, et al.
Publicado: (2013)

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition
por: Wang, Jun, et al.
Publicado: (2019)

Tracking dendritic cell migration into lymph nodes by using a novel PET probe (18)F-tetrafluoroborate for sodium/iodide symporter
por: Lee, Sang Bong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hgnqp3eg42oeqvu8j6mp9a4rb6