Pharmacokinetic properties of radiolabeled mutant Interleukin-2v: a PET imaging study

Interleukin-2 (IL2) is a cytokine that can stimulate cytotoxic immune cells to attack infected and malignant cells. Unfortunately, IL2 can also cause serious immune-related toxicity. Recently, a mutant of IL2 (IL2v) with abolished CD25 binding, increased plasma half-life and less toxicity was engine...

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Detalles Bibliográficos
Autores principales: Hartimath, Siddesh V., Manuelli, Valeria, Zijlma, Rolf, Signore, Alberto, Nayak, Tapan K., Freimoser-Grundschober, Anne, Klein, Christian, Dierckx, Rudi A.J.O., de Vries, Erik F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805544/
https://www.ncbi.nlm.nih.gov/pubmed/29467958
http://dx.doi.org/10.18632/oncotarget.23852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805544/
https://www.ncbi.nlm.nih.gov/pubmed/29467958
http://dx.doi.org/10.18632/oncotarget.23852

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