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Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer
Androgen receptor (AR) is a transcriptional activator that, in prostate cells, stimulates gene expression required for various cellular functions, including metabolisms and proliferation. AR signaling is also essential for the development of hormone-dependent prostate cancer (PCa) and its activity c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805650/ https://www.ncbi.nlm.nih.gov/pubmed/29059155 http://dx.doi.org/10.1038/onc.2017.385 |