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Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1

Organic Anion-Transporting Polypeptides are multispecific membrane proteins that regulate the passage of crucial endobiotics and drugs across pharmacological barriers. OATP1B1 and OATP1B3 have been described to play a major role in the hepatic uptake of statins, antivirals and various chemotherapeut...

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Detalles Bibliográficos
Autores principales:	Patik, Izabel, Székely, Virág, Német, Orsolya, Szepesi, Áron, Kucsma, Nóra, Várady, György, Szakács, Gergely, Bakos, Éva, Özvegy-Laczka, Csilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805760/ https://www.ncbi.nlm.nih.gov/pubmed/29422623 http://dx.doi.org/10.1038/s41598-018-20815-1

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