A critical role of E2F transcription factor 2 in proinflammatory cytokines-dependent proliferation and invasiveness of fibroblast-like synoviocytes in rheumatoid Arthritis

As a transcription factor, E2F2 participates in regulation of numerous genes. To investigate the role and mechnism of E2F2 in RA, expression of E2F2 in synovial tissue was detected. Proliferation, invasion, and secretion of inflammatory cytokines were measured after E2F2 was knocked-down in RASFs by...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Wang, Lin, Pan, Ji-hong, Han, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805761/
https://www.ncbi.nlm.nih.gov/pubmed/29422529
http://dx.doi.org/10.1038/s41598-018-20782-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805761/
https://www.ncbi.nlm.nih.gov/pubmed/29422529
http://dx.doi.org/10.1038/s41598-018-20782-7

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