Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito, when they are ingested in an infectious blood meal. Here, we determine the transmission-reducing activity (TRA) of naturally acquired antibodies from 648 malaria-exposed individuals using lab-based mosqui...

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Detalles Bibliográficos
Autores principales: Stone, Will J. R., Campo, Joseph J., Ouédraogo, André Lin, Meerstein-Kessel, Lisette, Morlais, Isabelle, Da, Dari, Cohuet, Anna, Nsango, Sandrine, Sutherland, Colin J., van de Vegte-Bolmer, Marga, Siebelink-Stoter, Rianne, van Gemert, Geert-Jan, Graumans, Wouter, Lanke, Kjerstin, Shandling, Adam D., Pablo, Jozelyn V., Teng, Andy A., Jones, Sophie, de Jong, Roos M., Fabra-García, Amanda, Bradley, John, Roeffen, Will, Lasonder, Edwin, Gremo, Giuliana, Schwarzer, Evelin, Janse, Chris J., Singh, Susheel K., Theisen, Michael, Felgner, Phil, Marti, Matthias, Drakeley, Chris, Sauerwein, Robert, Bousema, Teun, Jore, Matthijs M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805765/
https://www.ncbi.nlm.nih.gov/pubmed/29422648
http://dx.doi.org/10.1038/s41467-017-02646-2

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