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Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells
Deregulated signal transduction and energy metabolism are hallmarks of cancer and both play a fundamental role in tumorigenesis. While it is increasingly recognised that signalling and metabolism are highly interconnected, the underpinning mechanisms of their co-regulation are still largely unknown....
Autores principales: | Gonçalves, Emanuel, Sciacovelli, Marco, Costa, Ana S.H., Tran, Maxine Gia Binh, Johnson, Timothy Isaac, Machado, Daniel, Frezza, Christian, Saez-Rodriguez, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805855/ https://www.ncbi.nlm.nih.gov/pubmed/29191787 http://dx.doi.org/10.1016/j.ymben.2017.11.011 |
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