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Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1

OBJECTIVES: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. MATERIAL AND METHODS: The panoramic radiographs of 179 patients were analysed for supernumerary molars an...

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Autores principales: Friedrich, Reinhard E., Reul, Anika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Stilus Optimus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806042/
https://www.ncbi.nlm.nih.gov/pubmed/29435207
http://dx.doi.org/10.5037/jomr.2017.8405
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author Friedrich, Reinhard E.
Reul, Anika
author_facet Friedrich, Reinhard E.
Reul, Anika
author_sort Friedrich, Reinhard E.
collection PubMed
description OBJECTIVES: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. MATERIAL AND METHODS: The panoramic radiographs of 179 patients were analysed for supernumerary molars and dysplastic wisdom teeth with special reference to facial tumour type. The results were compared to radiographic findings obtained in panoramic radiographs of age- and sex-matched controls. RESULTS: The total number of dysplastic or supernumerary molars was 21 (17 individuals, 4.75%) and predominantly a finding of the maxilla (maxilla: 15, mandible: 1, maxilla and mandible: 1). Differences of dental findings between neurofibromatosis type 1 (NF1) patients (n = 15) and the control group (n = 2) were statistically significant (P < 0.01). All individuals with supernumerary molars were diagnosed as being affected with NF1. This difference achieved statistical significance when it was considered that the event may occur at least once per quadrant, and thus the individual potentially needs to be considered four times (P = 0.0038). CONCLUSIONS: This investigation revealed that supernumerary molars and aberrations in wisdom tooth form are more common in patients than in age- and sex-matched controls. There is no association between these findings and a specific feature of the disease, id est facial manifestation of a trigeminal nerve sheath tumour (plexiform neurofibroma). The cause of this phenomenon is unknown. A review of these dental findings on other neurofibromatosis type 1 study groups should be attempted.
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spelling pubmed-58060422018-02-12 Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1 Friedrich, Reinhard E. Reul, Anika J Oral Maxillofac Res Original Paper OBJECTIVES: The purpose of the present study was the systematic investigation of numerical and morphological aberrations of teeth in the wisdom teeth region in neurofibromatosis type 1 patients. MATERIAL AND METHODS: The panoramic radiographs of 179 patients were analysed for supernumerary molars and dysplastic wisdom teeth with special reference to facial tumour type. The results were compared to radiographic findings obtained in panoramic radiographs of age- and sex-matched controls. RESULTS: The total number of dysplastic or supernumerary molars was 21 (17 individuals, 4.75%) and predominantly a finding of the maxilla (maxilla: 15, mandible: 1, maxilla and mandible: 1). Differences of dental findings between neurofibromatosis type 1 (NF1) patients (n = 15) and the control group (n = 2) were statistically significant (P < 0.01). All individuals with supernumerary molars were diagnosed as being affected with NF1. This difference achieved statistical significance when it was considered that the event may occur at least once per quadrant, and thus the individual potentially needs to be considered four times (P = 0.0038). CONCLUSIONS: This investigation revealed that supernumerary molars and aberrations in wisdom tooth form are more common in patients than in age- and sex-matched controls. There is no association between these findings and a specific feature of the disease, id est facial manifestation of a trigeminal nerve sheath tumour (plexiform neurofibroma). The cause of this phenomenon is unknown. A review of these dental findings on other neurofibromatosis type 1 study groups should be attempted. Stilus Optimus 2017-12-31 /pmc/articles/PMC5806042/ /pubmed/29435207 http://dx.doi.org/10.5037/jomr.2017.8405 Text en Copyright © Friedrich RE, Reul A. Published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH (http://www.ejomr.org), 31 December 2017. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article, first published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH, distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 UnportedLicense (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work and is properly cited. The copyright, license information and link to the original publication on (http://www.ejomr.org) must be included.
spellingShingle Original Paper
Friedrich, Reinhard E.
Reul, Anika
Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_full Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_fullStr Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_full_unstemmed Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_short Supernumerary Molars and Wisdom Tooth Shape Alterations in Patients with Neurofibromatosis Type 1
title_sort supernumerary molars and wisdom tooth shape alterations in patients with neurofibromatosis type 1
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806042/
https://www.ncbi.nlm.nih.gov/pubmed/29435207
http://dx.doi.org/10.5037/jomr.2017.8405
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