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Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes
BACKGROUND: Follicle stimulating hormone and testosterone stimulate Sertoli cells to support germ cell function and differentiation. During mini-puberty, when gonadotropin (GnRH) stimulates increases in plasma luteinizing hormone (LH) and testosterone levels, gonocytes are transformed into Ad sperma...
Autores principales: | Gegenschatz-Schmid, Katharina, Verkauskas, Gilvydas, Demougin, Philippe, Bilius, Vytautas, Dasevicius, Darius, Stadler, Michael B., Hadziselimovic, Faruk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806254/ https://www.ncbi.nlm.nih.gov/pubmed/29456864 http://dx.doi.org/10.1186/s12610-018-0067-1 |
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