Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms

BACKGROUND: Hyperammonemic rats reproduce the cognitive alterations of patients with hepatic encephalopathy, including altered spatial memory, attributed to altered membrane expression of AMPA receptor subunits in hippocampus. Neuroinflammation mediates these cognitive alterations. We hypothesized t...

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Detalles Bibliográficos
Autores principales: Taoro-Gonzalez, Lucas, Arenas, Yaiza M., Cabrera-Pastor, Andrea, Felipo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806265/
https://www.ncbi.nlm.nih.gov/pubmed/29422059
http://dx.doi.org/10.1186/s12974-018-1082-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806265/
https://www.ncbi.nlm.nih.gov/pubmed/29422059
http://dx.doi.org/10.1186/s12974-018-1082-z

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