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Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms
BACKGROUND: Hyperammonemic rats reproduce the cognitive alterations of patients with hepatic encephalopathy, including altered spatial memory, attributed to altered membrane expression of AMPA receptor subunits in hippocampus. Neuroinflammation mediates these cognitive alterations. We hypothesized t...
Autores principales: | Taoro-Gonzalez, Lucas, Arenas, Yaiza M., Cabrera-Pastor, Andrea, Felipo, Vicente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806265/ https://www.ncbi.nlm.nih.gov/pubmed/29422059 http://dx.doi.org/10.1186/s12974-018-1082-z |
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