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Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin

BACKGROUND: Cutaneous basal cell carcinoma (BCC) is the commonest cancer worldwide. BCC is locally invasive and the surrounding stromal microenvironment is pivotal for tumourigenesis. Cancer associated fibroblasts (CAFs) in the microenvironment are essential for tumour growth in a variety of neoplas...

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Detalles Bibliográficos
Autores principales: Omland, Silje Haukali, Wettergren, Erika Elgstrand, Mourier, Tobias, Hansen, Anders Johannes, Asplund, Maria, Mollerup, Sarah, Robert, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806272/
https://www.ncbi.nlm.nih.gov/pubmed/28987144
http://dx.doi.org/10.1186/s12885-017-3663-0