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Heterologous and endogenous U6 snRNA promoters enable CRISPR/Cas9 mediated genome editing in Aspergillus niger

BACKGROUND: U6 promoters have been used for single guide RNA (sgRNA) transcription in the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas9) genome editing system. However, no available U6 promoters have been identified in Aspergillus niger, which is an...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiaomei, Zheng, Ping, Sun, Jibin, Kun, Zhang, Ma, Yanhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806293/ https://www.ncbi.nlm.nih.gov/pubmed/29456867 http://dx.doi.org/10.1186/s40694-018-0047-4

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