Is RNASEL:p.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

BACKGROUND: Breast cancer risk for BRCA1 and BRCA2 pathogenic mutation carriers is modified by risk factors that cluster in families, including genetic modifiers of risk. We considered genetic modifiers of risk for carriers of high-risk mutations in other breast cancer susceptibility genes. METHODS:...

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Detalles Bibliográficos
Autores principales: Nguyen-Dumont, Tú, Teo, Zhi L., Hammet, Fleur, Roberge, Alexis, Mahmoodi, Maryam, Tsimiklis, Helen, Park, Daniel J., Pope, Bernard J., Lonie, Andrew, Kapuscinski, Miroslav K., Mahmood, Khalid, Goldgar, David E., Giles, Graham G., Winship, Ingrid, Hopper, John L., Southey, Melissa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806316/
https://www.ncbi.nlm.nih.gov/pubmed/29422015
http://dx.doi.org/10.1186/s12885-018-4028-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806316/
https://www.ncbi.nlm.nih.gov/pubmed/29422015
http://dx.doi.org/10.1186/s12885-018-4028-z

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