Genome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys

BACKGROUND: Previous studies showed that the majority of developmental genes are devoid of DNA methylation at promoters even when they are repressed. Such hypomethylated regions at developmental genes are unusually large and extend well beyond proximal promoters, forming DNA methylation valleys (DMV...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Zheng, Hui, Wang, Qiujun, Zhou, Chen, Wei, Lei, Liu, Xuehui, Zhang, Wenhao, Zhang, Yu, Du, Zhenhai, Wang, Xiaowo, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806489/
https://www.ncbi.nlm.nih.gov/pubmed/29422066
http://dx.doi.org/10.1186/s13059-018-1390-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806489/
https://www.ncbi.nlm.nih.gov/pubmed/29422066
http://dx.doi.org/10.1186/s13059-018-1390-8

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