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Estimating kinetic mechanisms with prior knowledge II: Behavioral constraints and numerical tests
Kinetic mechanisms predict how ion channels and other proteins function at the molecular and cellular levels. Ideally, a kinetic model should explain new data but also be consistent with existing knowledge. In this two-part study, we present a mathematical and computational formalism that can be use...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806673/ https://www.ncbi.nlm.nih.gov/pubmed/29321263 http://dx.doi.org/10.1085/jgp.201711912 |