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Nonsensing residues in S3–S4 linker’s C terminus affect the voltage sensor set point in K(+) channels

Voltage sensitivity in ion channels is a function of highly conserved arginine residues in their voltage-sensing domains (VSDs), but this conservation does not explain the diversity in voltage dependence among different K(+) channels. Here we study the non–voltage-sensing residues 353 to 361 in Shak...

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Detalles Bibliográficos
Autores principales: Carvalho-de-Souza, Joao L., Bezanilla, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806678/
https://www.ncbi.nlm.nih.gov/pubmed/29321262
http://dx.doi.org/10.1085/jgp.201711882