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Nonsensing residues in S3–S4 linker’s C terminus affect the voltage sensor set point in K(+) channels
Voltage sensitivity in ion channels is a function of highly conserved arginine residues in their voltage-sensing domains (VSDs), but this conservation does not explain the diversity in voltage dependence among different K(+) channels. Here we study the non–voltage-sensing residues 353 to 361 in Shak...
Autores principales: | Carvalho-de-Souza, Joao L., Bezanilla, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806678/ https://www.ncbi.nlm.nih.gov/pubmed/29321262 http://dx.doi.org/10.1085/jgp.201711882 |
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