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Molecular determinants of pH regulation in the cardiac Na(+)–Ca(2+) exchanger

The cardiac Na(+)–Ca(2+) exchanger (NCX) plays a critical role in the heart by extruding Ca(2+) after each contraction and thus regulates cardiac contractility. The activity of NCX is strongly inhibited by cytosolic protons, which suggests that intracellular acidification will have important effects...

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Detalles Bibliográficos
Autores principales:	John, Scott, Kim, Brian, Olcese, Riccardo, Goldhaber, Joshua I., Ottolia, Michela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806679/ https://www.ncbi.nlm.nih.gov/pubmed/29301861 http://dx.doi.org/10.1085/jgp.201611693

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